Zopiclone 3,75 mg Milpharm 28 tablets.


Zopiclone 3,5 mg Milpharm 28 tablets.

Manufacturer: Milpharm
Basic substance : Zopiclone.
Package : 3,5mg.tab x 28tabs.

Zopiclone is a tranquilliser drug. It works by causing a depression or tranquillisation of the Central Nervous System. As zopiclone is sedating it is marketed as a sleeping pill.



Zopiclone 3,75 mg Milpharm 28 tablets.

Zopiclone 3,75 mg is a hypnotic and sedative which is used in severe sleep disorder. This medicine may increase the risk of habit-forming tendency if taken for a long duration or at larger doses. Do not stop abruptly taking this medicine as it may cause withdrawal symptoms like convulsions, behavioral disorders, anxiety, etc. This medicine is not recommended for use in patients below 18 years of age.

Medication for Insomnia is a true relief for many of us and can finally be rested again. In any case, it is important that the drug should be taken according to the instructions and thus the risk of side effects is prevented. That is often a fear point in people who are prescribed such a medicine. However, by gathering more information about how Zopiclone 3,75 mg works and all its possible effects on the body, it can be safely taken.
An exception within the group of sleeping pills.

Zopiclone 3,75 mg is rapidly absorbed from the gastrointestinal tract. Cmax is reached within 1 to 1.5 hours and plasma protein binding is approximately 45%. Easily passes through histohematogenous barriers, including BBB, and is distributed to organs and tissues, incl. brain. Passes through the placental barrier, enters breast milk (breast milk contains 2 times lower concentrations than blood plasma). It is metabolized in the liver with the formation of N-oxide, which has low pharmacological activity, and 2 inactive metabolites. T1 / 2 – 3.5-6 hours, with severe hepatic failure that passes to 11 hours. It is mainly excreted by the kidneys as metabolites (80%), as well as by the intestines (16%). There is information about the excretion of small amounts by the salivary glands. Repeated doses are not accompanied by an accumulation of zopiclone and its metabolites.

It shortens the period of falling asleep, reduces the number of nocturnal awakenings, improves the quality of sleep, does not change the structure of the phases of sleep. It is effective for situational insomnia associated with psycho-emotional stress, changes in the usual rhythm of life (for example, during hospitalization), desynchronosis, incl. when changing time zone, changing operating mode. Sleep occurs within 20 to 30 minutes of ingestion and lasts 6 to 8 hours.


Dosage :

The usual starting dose is 3.75 mg taken just before bedtime when required to help with difficulty sleeping. The recommended adult dose of zopiclone ranges from 3.75 mg to 7.5 mg. The maximum daily dose is 5 mg for seniors, people with reduced liver or kidney function, and people taking certain medications. This medication may be habit-forming and should be taken exactly as prescribed by your doctor. You should not typically use zopiclone for more than 7 to 10 days in a row.

If you have been taking this medication regularly for an extended period of time, do not stop taking it suddenly without talking with your doctor.

Many things can affect the dose of a medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here,do not change the way that you are taking the medication without consulting your doctor.

It is important to take this medication exactly as prescribed by your doctor. Do not take this medication when a full night’s sleep is not possible or before you would need to be active and functional. Impaired judgement and memory lapses may occur in such situations. Your body needs time to eliminate the medication from your system. Wait at least 12 hours after taking this medication before driving or engaging in other activities that require mental alertness.

Store this medication at room temperature, protect it from light and moisture, and keep it out of the reach of children.

Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.


Side effects :

Zopiclone 3,75 mg ; Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

More common
– confusion—more common in older adults
– clumsiness or unsteadiness—more common in older adults
– daytime anxiety and/or restlessness
– difficulty with coordination—more common in older adults
– mood or mental changes

Less common
– Drowsiness (severe)
– shortness of breath
– ndifficult or labored breathing
– tightness in chest
– wheezing
– skin rash
– aggressiveness
– behavior changes


– Memory problems—more common in older patients
– behavior or mental changes


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